Dean Charles DeLisi's research centers on computational problems that arise in
determining the structure and function of large biological molecules and the
design of molecular architectures with specified activity. Problems of interest
include the structural basis of signal transduction by membrane bound
receptors, the structural basis of voltage gating, and the docking of peptide
hormones and neurotransmitters at their sites of action. Other projects involve
the use of large databases to develop expert systems and train neural networks
for the problem of rapidly identifying regions of key importance in DNA and
proteins. Dean Delisi has written widely in the field and has recently
published articles in the Physics Review of Letters, the Biophysical
Journal, and Computing in Science and Engineering.
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