Models of Human Disease that are Constrained by Current Animal and Cell Culture Models
Investigation of a number of
human diseases is severely constrained by a lack of in vitro models. A number of pathogenic viruses including
human immunodeficiency virus and hepatitis C virus grow only in human or
chimpanzee cells. ES cells might provide cell and tissue types that will
greatly accelerate investigation into these and other viral diseases. Current
animal models of neurodegenerative diseases such as Alzheimer’s disease give
only a very partial representation of the disease’s process.
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| Contributed by: AAAS DoSER and the Institute for
Civil Society
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